Caution: At least an order of magnitude frame rate drop noticed when using resident buffers (aka Bindless) registered with CUDA. From more than 150 fps to just 1 fps, even if no CUDA manipulation executed (just registering). The behavior exposed on 260.99 and 261.00 drivers on both Vista 32-bit and Windows7 64-bit. On XP 32-bit everything works correctly!
Long life to XP!